The USS Nautilus (NCC-31910) was a Miranda-class starship active in the late 24th century. During the Dominion War, the Nautilus participated in several campaigns. One noteworthy campaign was the First Battle of Chin'toka in late 2374, where the Nautilus was among three ships assisting the USS Defiant in destroying the power generator for the Dominion orbital weapons platforms. (DS9: "Tears of the Prophets")