USS Little (DD-79/APD-4), a Wickes-class destroyer in the United States Navy during the World War I and World War II. She was the first Navy ship named for George Little (1754–1809). Little was laid down by Fore River Shipbuilding Corporation, Quincy, Massachusetts, June 18, 1917, launched November 11, 1917, sponsored by Mrs. Samuel W. Wakeman, and commissioned April 6, 1918, Commander Joseph K. Taussig in command.