Dying Changes Everything is the first episode of the 5th season of House which first aired on September 16, 2008. The team treats the assistant of a powerful woman and Thirteen starts to see something of her own nature in the patient’s subordination to her employer. In grief over Amber's death, Wilson contemplates resigning from the hospital. When House reacts by telling him to get over it, their friendship is strained to the point where Cuddy has to be called in to do the equivalent of couples counselling. However, when push comes to shove, it appears that House may have to choose between his friendship with Wilson, the life of his patient, or his job at Princeton-Plainsboro.