USS Goldsborough (DD-188/AVP-18/AVD-5/APD-32) was a Clemson-class destroyer in the United States Navy during World War II. She was the second Navy ship named for Rear Admiral Louis M. Goldsborough (1805–1877). Goldsborough was launched 20 November 1918 by the Newport News Shipbuilding & Dry Dock Company, Newport News, Virginia; sponsored by Miss Lucetta Pennington Goldsborough, daughter of R.Adm. Goldsborough; commissioned at Norfolk, Virginia 26 January 1920, Commander Francis M. Robinson in command.