An evil organization of lizared-themed super-villians run by King Lizard. They are responsible for the deaths of Kate Cha and Shrinking Ray. The league was first seen attacking a building and trying to steal some kind of canister, but was easily stopped by Invincible and Atom Eve. The leader, King Lizard, swore this wouldn't be the last time Invincible saw them. The Lizard League was secretly being led by King Lizard even in jail, but when his order cease, Supreme Lizard tried to takeover until King Lizard returned and killed him. He revealed the reason his orders ceased was because he had escaped.