Francesco Barberini (November 12, 1662 – August 17, 1738) was Italian cardinal of the family of Pope Urban VIII (1623–1644) and of princes of Palestrina. He was created by Pope Alexander VIII on November 13, 1690 with the dispensation of having a cousin (Rinaldo d'Este) and uncle (Carlo Barberini) in the Sacred College and for not having yet received the minor orders. He was ordained deacon only in 1700 and priest in 1715. He participated in the five papal conclaves (1691, 1700, 1721, 1724 and 1730). Abbot of Farfa and Subiaco from 1704. He was Cardinal-Bishop of Palestrina (March 3, 1721 until July 1, 1726) and Cardinal-Bishop of Ostia e Velletri (July 1, 1726). Prefect of the Sacred Congregations of Bishops and Regulars and of Waters from 1726. Dean of the Sacred College of Cardinals in