In the Mushroom Kingdom Hospital, Dr. Mario was trying to perfect his formula for killing the Viruses when Luigi and Nurse Peach came in and scared Dr. Mario, causing him to drop his concoction all over his brand new lab coat. Dr. Mario took it off and put another one on as Peach told him that there were three more outbreaks of the Viruses in The Mushroom Kingdom. Dr. Mario sighed and told Peach and Luigi to close up the hospital for the day. So, after the viruses were all done dancing around, they sneaked into Dr. Mario's office.