Details: Mario Lozano is wanted for the murder of Isaac Guzman, 17, which occurred in Watsonville, California, on December 3, 2004. Lozano was dating Isaac's cousin Roxanne prior to the murder. When Isaac learned that Roxanne was being abused by Lozano, he confronted him. Several days later, on December 3, Lozano met Isaac in front of Isaac's high school and the two got into an argument. Lozano pulled out a knife and stabbed Isaac multiple times. Tragically, Isaac Guzman passed away at a nearby hospital. Lozano fled the scene and was later charged with murder.