USS Charrette (DD-581) was a Fletcher-class destroyer of the United States Navy, named for Lieutenant George Charrette (1867–1938), who was awarded the Medal of Honor for heroism during the Spanish-American War. Charrette was launched 3 June 1942 by the Boston Navy Yard, sponsored by Mrs. G. Charrette; and commissioned 18 May 1943, Commander E. S. Karpe in command.