The 1545-1546 was part of a failed attempt by the Uesugi clan to regain Kawagoe Castle from the Late Hōjō clan in the Sengoku Period of Japan. Uesugi Tomosada of the Ogigayatsu branch of the Uesugi clan was joined by his more powerful relative Uesugi Norimasa, by Ashikaga Haruuji, the Kantō Kubō in Koga, and by a host of anti-Hōjō daimyō from the Kantō region. The tactic succeeded, and the Hōjō foiled the siege. This defeat for the Uesugi would lead to the near-extinction of the family.