Lössl has appeared on-camera in episodes of the German series Der Alte, Derrick, and Tatort. She is the primary German voice of Penelope Cruz and Naomi Watts (including King Kong). She dubbed Drew Barrymore in Scream and other movies, Kristen Wiig in Adventureland and MacGruber, Marisa Tomei in Real Love, Renée Zellweger in Chicago, Halle Berry in Beverly Hills Beauties, and Ricki Lake in Mrs. Winterbourne. TV dub roles included Christina Applegate on Married... with Children, Paula Marshall on Out of Practice, Lena Headey on Game of Thrones, and Julie Bowen on Boston Legal.