Among Tower's earliest films were the John Ford motion pictures The Horse Soldiers and Sergeant Rutledge (with Jeffrey Hunter). Towers has also guest starred in Perry Mason, Hawaii Five-O (with John Colicos), The Outer Limits, Matlock (with Eric Pierpoint) and Frasier (with Kelsey Grammer). In 2007, she guest starred in Ira Steven Behr's series The 4400, as the title character in the episode "Audrey Parker Has Come And Gone".