In "Roger 'n' Me", Francine suffers from having her brain detached and needs an expensive operation but Stan is unable to raise the money. Roger ends up probing Dr. Gupta in order to learn how to do the operation himself. Dr. Gupta appears when Roger has a vision of Dr. Stack being fired by Dr. Baby in "Vision: Impossible". Tired of sitting in the lobby, Stan snaps a picture under his shirt and sends a text to Dr. Gupta in "Seizures Suit Stanny", wanting to know if it is a mole. She responds back that it is his nipple. Dr. Gupta is voiced by Laura Linney.