Garci Lasso Ruiz de la Vega (1340 – 2 April 1367) was a Spanish noble from Cantabria and one of the pillars in the glorious and tragic history of the prominent contemporary House of Garci Lasso de la Vega or Garcilasco de la Vega. As the eldest son Garci Lasso Ruiz de la Vega succeeded his father, Garci Lasso de la Vega II, as the head of his household.