John Guise (1682 or 1683 – 12 June 1765) was a British Army officer and art collector. He obtained a practical knowledge of the profession of arms in the wars of Queen Anne. He served many years in the 1st Regiment of Foot Guards, and was promoted to the lieutenant-colonelcy of that regiment in 1736. On 1 November 1738 King George II rewarded him with the colonelcy of the 6th Regiment of Foot. In 1739 he was promoted to the rank of brigadier-general, in 1742 to that of major-general, in 1745 to that of lieutenant-general, and in 1762 to that of general. He held the appointment of governor of Berwick several years, and died in June 1765.