The 1925 Rochester Jeffersons season was their sixth and final season in the National Football League. The team improved on their previous output of 0–7, losing only six games and logging a tie. They tied for sixteenth in the league. In 1925, though, their scoring output improved, being outscored by a margin of only 111-26. Despite the improvement both on offense and defense, the team finished without a victory for the fourth consecutive season. This streak of 23 games without a victory is topped only by 1976-77 Tampa Bay Buccaneers (26 consecutive losses).