Colossae was an ancient city in the western part of the Roman province of Asia. It was about 12 miles southeast of Laodicea on the road that lead from Ephesus to the Euphrates River in the east. It was located in the valley of the Lycus River, roughly 100 miles east of Ephesus. Based on the evidence, Paul sent Tychicus with letters to assemblies along the road from Ephesus to Colossae and, perhaps, to the province of Galatia. This would have included Ephesians, Colossians, Philemon, and the letter "from" the church at Laodicea.