The Saishū Ketsugan has all of the abilities of the Ketsugan, in addition to its unique abilities. The first ability of the Saishū Ketsugan is that it nullifies any and all genjutsu cast on the wielder, in effect making them immune to genjutsu. With practice, the user can reflect genjutsu cast on them back at the user, from D-Ranked genjutsu to the likes of the great Tsukuyomi.