Keyes' film credits included Friday the 13th, Zapped, Frankenstein General Hospital (as the monster), The Private Eyes (with Don Knotts), Timemaster, House of 1,000 Corpses (as Ravelli, named after a Marx Brothers character), and Intolerable Cruelty. On television, he was a recurring guest on The Jeffersons as genially dim-witted bodyguard Hugo Mojelewski, and also appeared on Growing Pains, Police Squad! (with Leslie Nielsen), EZ Streets, and Black Scorpion.