The Millefiore Famiglia is the most powerful Mafia Famiglia in the world when depicted in the Future Arc of the series 9 years and 10 months after the present day. The Millefiore Famiglia is made up of two groups: the Black Spell and White Spell, both of which were formerly two separate Famiglias, the Giglio Nero Famiglia and Gesso Famiglia, respectively, the former withdrawing after Yuni awakened from Byakuran's drug.