Nicole "Niki" Sanders was a former casino worker in Las Vegas. She was raising her son, Micah, alone because her husband D.L. was a fugitive. In the absence of D.L. and his regular paycheck from construction work, she earned extra money as a webcam stripper running lasvegasniki.com. She had an aggressive alter-ego named Jessica, under whose identity violent acts and murders were committed. After the events at Kirby Plaza, Niki worked as an agent of the Company and was infected with the Shanti virus. As the virus progressed, Niki returned to New Orleans to stay with Micah. She was later killed in an explosion after she saved Monica Dawson.