USS Halford (DD-480), a Fletcher-class destroyer, was a ship of the United States Navy named for Lieutenant William Halford (1841–1919), a recipient of the Medal of Honor. Halford was laid down on 3 June 1941 at the Puget Sound Navy Yard, Bremerton, Washington; launched on 29 October 1942, sponsored by Miss Eunice Halford, daughter of Lieutenant Halford; and commissioned on 10 April 1943, with Lieutenant Commander G. N. Johansen in command.