Alpha-Omega (Chinese: 阿尔法欧米茄 Ā'ěrfǎ ōumǐjiā) also known under the symbols α-Ω, is a deadly Bio Weapon. It was created by BTHK Biotech in Hong Kong. It consists of two corresponding parts; Alpha and Omega. General Matthew Shrieve used it to kill thousands of innocent people in Hong Kong including Akio Yamashiro. Later Maseo Yamashiro handed over the bio weapon to Ra's al Ghul which Nyssa al Ghul hid it in the handle of her weapon. After capturing Nyssa, Ra's gave the virus to Oliver telling him to destroy his city. Ra's used it to kill many innocent people of Starling City but they were cured by Ray Palmer with his nano-tech.