Luke Pryor Blackburn (June 16, 1816September 14, 1887) was an American physician, philanthropist, and politician from Kentucky. He was elected the 28th governor of Kentucky, serving from 1879 to 1883. Until the election of Ernie Fletcher in 2003, Blackburn was the only physician to serve as governor of Kentucky. After earning a medical degree at Transylvania University, Blackburn moved to Natchez, Mississippi, and gained national fame for implementing the first successful quarantine against yellow fever in the Mississippi River valley in 1848. He came to be regarded as an expert on yellow fever and often worked pro bono to combat outbreaks. Among his philanthropic ventures was the construction of a hospital for boatmen working on the Mississippi River using his personal funds. He later suc