Formerly known as the Scorpion, Mac Gargan later became the host of the Venom symbiote, an alien being that gives its host superhuman strength, regeneration, and an intense hatred of Spider-Man. When he tracked down Miles Morales' father for revenge, Spider-Man (Miles) came to the rescue. However, Spider-Man's effort wasn't enough to keep his parents from being killed. With all his effort, Spider-Man took Mac Gargan down using his venom blasts to paralyze him.