In 2368, an EPS relay ruptured behind a wall in the cargo bay aboard the USS Enterprise-D when the ship ran into a quantum filament, and the conduit ignited into a plasma fire. Dr. Crusher and Commander La Forge were trapped in the cargo bay and put out the fire by opening the cargo bay doors to space. (TNG: "Disaster" ) In 2372, a plasma fire broke out in the engine room of the USS Defiant. (DS9: "Rejoined")