USS Helen Euphane (SP-403) was a United States Navy patrol vessel and minesweeper in commission from 1917 to 1919. Helen Euphane was built as a commercial fishing boat of the same name in 1902 by E. J. Tull at Pocomoke City, Maryland. On 23 May 1917, the U.S. Navy purchased her from the Eubank Tankard Company of Kilmarnock, Virginia, for use as a section patrol vessel and minesweeper during World War I. The Eubank Tankard Company delivered her to the Navy on 5 June 1917. Her first commanding officer was Lieutenant, junior grade, Rowland G. Foster, USNRF.