Otis Sistrunk (born September 18, 1946 in Columbus, Georgia) is a former professional football player who played seven seasons as a defensive lineman, from 1972 to 1978. He played his entire National Football League (NFL) career with the Oakland Raiders. Sistrunk later became a professional wrestler in the National Wrestling Alliance (NWA). He is a distant cousin to former NFL player Manny Sistrunk.