Isis canyon was one of the largest and loneliest stretches of desert on the planet of Bellerophon. When the crew of Serenity performed a heist on the Bellerophon states, Kaylee Frye reprogrammed a computerized waste disposal bin to drop off their hidden booty (the Lassiter, which was stored in the waste) within the canyon, which was the loneliest piece of land Hoban Washburne could find on the planet.