George Thomas Saimes (September 1, 1941 – March 8, 2013) was an American football defensive back and fullback for Michigan State University and the Buffalo Bills of the American Football League, which produced American Football League Championships in 1964 and 1965. He achieved All-American Football League honors five times, and is a member of the American Football League All-Time Team, the Buffalo Bills' Wall of Fame, and the Greater Buffalo Sports Hall of Fame.