Grigorios Spandidakis (, 1909–1996) was a Greek Army officer who rose to the rank of Lieutenant General and the post of Chief of the Hellenic Army General Staff in 1965–1967. From this position, he was instrumental in the military preparations that resulted in the coup d'état of 21 April 1967 and the establishment of the Regime of the Colonels. He served as Deputy Prime Minister and Minister for National Defence in the first government of the new regime, but was dismissed after supporting the failed counter-coup attempt launched by King Constantine II on 13 December 1967. After the fall of the regime, he was tried and convicted to life imprisonment for his role in it. He secured an early release on health grounds and died in 1996.