USS Harding (DD-91) was a Wickes-class destroyer in the United States Navy during World War I. She was the first ship named in honor of Seth Harding. Launched in 1918, she undertook training exercises off the East Coast of the United States sporadically for several years. In 1919, she escorted a major transatlantic flight of Curtiss NC seaplane. Later that year, she was selected to be converted into a seaplane tender, and was then used to support naval aviator training off Naval Air Station Pensacola. She took one trip to Veracruz with emergency medical supplies, and was also on hand during aircraft bombing tests against decommissioned German ships, including the sinking of the SMS Ostfriesland. She was decommissioned in 1922 and sold for scrapping in 1936.