Sometime after their defeat in the past, the group called Mad Gear are back on a worldwide scale under Retu's leadership. To take revenge on Guy, the Mad Gear gang starts with kidnapping both Genryusai and Rena - Maki's father and sister. With Guy (Rena's fiancé and Genryusai's student) off training and unable to help, Maki enlists the help of Haggar and Carlos. The three embark on a global search to look for her family's whereabouts and save them while dissolving all of Mad Gear's groups during their journey.