Friedlob's worked as a writer or story editor on various animated series, notably for Hanna-Barbera: Shirt Tales, The Biskitts, The Smurfs, The Snorks, Pink Panther and Sons, SuperFriends, and three different Scooby-Doo series. Other credits included Alvin & the Chipmunks, Kissyfur and the animated Kid 'n Play series. The latter, again working with John Semper, led to the screenplay of Kid 'n Play's 1992 feature film Class Act. In more recent years, Friedlob has exhibited her work as a visual artist and hosted the radio show Experience Talks over KPFK-FM in Los Angeles.