HMCS Mackenzie (DDE 261) was a Mackenzie-class destroyer that served in the Royal Canadian Navy and later the Canadian Forces. She was the lead ship of her class and is the first Canadian naval unit to carry this name. Mackenzie was laid down on 15 December 1958 at Canadian Vickers Ltd., Montreal and launched on 25 May 1961. She was commissioned into the RCN on 6 October 1962. She was assigned to the Pacific Fleet and served largely as a training ship with the RCN and later in the CF under Maritime Forces Pacific (MARPAC). She underwent the Destroyer Life Extension Project (DELEX) in 1985.