Interstate 40 is a United States interstate running from Barstow, California to North Carolina. Interstate 40 appears in Cars. Lightning McQueen and Mack start their drive to Los Angeles from the Motor Speedway of the South, and are seen afterwards driving west on the Interstate during the "Life is a Highway" sequence. The interstate is responsible for bypassing Radiator Springs (to save 10 minutes of driving, according to Sally) causing Radiator Springs to lose all its visitors and customers. The Top Down Truckstop is located along Interstate 40.