Xylakant made a sequel to this flash on June 12, 2006, simply titled Meaning Of Life 2006 P.2, which, however, does not include a screamer. Instead, it's a simple joke animation about Tom Fulp (founder of Newgrounds.com) and his brother Wade, represented by moving photos, creating an animation containing a bawdy “song”, which includes some adult imagery. Both the dialogue and the song are narrated by Microsoft Sam.