Jailor's Pox is an affliction that is mostly involved in Bethan the Biologist's story mission in Player-owned ports. Bethan recovers samples from a disease-riddled abandoned ship found in The Scythe region, and deliberately infects Finia with it under controlled conditions in order to test and examine the natural resistances of sea orphans, but Finia escaped quarantine and infected other sea orphans on Hyu-Ji, where the disease mutated enough that it was able to overcome their natural resistances and plagued the island.