She married Colonel John Jacob Astor IV, son of William Backhouse Astor, Jr. and Caroline Webster "Lina" Schermerhorn, on February 17, 1891 in Philadelphia, Pennsylvania. The newlywed couple was given, among many lavish gifts, a furnished townhouse on Fifth Avenue in New York City. Though the marriage was tumultuous, the Astors had two children, William Vincent Astor (b. Nov 15, 1891) and Ava Alice Muriel Astor (b. July 7, 1902).