Manase Jesse Sapolu (born March 10, 1961) is a former football player in the National Football League. Sapolu played both center and offensive guard, and spent his entire career in a San Francisco 49ers uniform. Jesse Sapolu attended Farrington High School and the University of Hawaii in Honolulu. Standing 6 feet 4 inches, 278 lbs., he was selected by the Oakland Invaders in the 17th round (199th pick overall) of the 1983 USFL draft, and selected by San Francisco 49ers in the 11th round (289th pick overall) of the 1983 NFL draft. He signed with the San Francisco 49ers on July 10, 1983.