Symbology or Runology appear in Star Ocean 3: Till the End of Time as an ability available to most playable characters, but most prominently wielded by Sophia Esteed, Adray Lasbard and Nel Zelpher, with Fayt Leingod and Maria Traydor learning various destructive and augmentative spells, respectively, in accordance with the powers afforded them by Symbological Genetics. Although Sophia's outstanding abilities as a symbologist are never fully explained, it may be presumed that she, too, was granted her powers by the research conducted upon her in her infancy.