Hamster Number 1 was a small hamster used as a test subject at the Enriched Learning Center for Gifted Children that appeared during Bart the Genius. Cecile Shapiro was fond of the hamsters; She infected Hamster Number 1 with the straphococcoli virus to test, while Hamster Number 2 acted as the control hamster. Bart accidentally blew the school apart and it, along with Hamster Number 2, escaped.