Established as a B-17 Flying Fortress heavy bomber squadron; trained under Second Air Force. Deployed to European Theater of Operations (ETO), assigned to VIII Bomber Command in England, Flew combat missions over Nazi Germany and Occupied Europe until the German capitulation in May 1945. Activated as a reserve B-29 Superfortress squadron, 1947. Not equipped or manned; inactivated due to budget reductions, 1949. Reactivated in 1986 as a B-1B Lancer training squadron, assuming assets of 4018th Combat Crew Training Squadron which was activated in 1985 when B-1s first arrived at Dyess.