Marcus Nonius Macrinus was a Roman general and statesman fl. 161 AD in the era of Emperor Marcus Aurelius. He served as Consul (suffectus) in 154, and several terms as proconsul thereafter. According to the inscriptions on his tomb, he was originally from Brescia. During his lifetime, he served not only as an adviser to Marcus Aurelius, but also as proconsul of the Roman province of Asia.