If anything approaches a Cryo Vine, it will shrivel slightly and release a cryo mist that has a high chance of causing a cryo damage-over-time, causing Vault Hunters to slow down and freezable enemies to be frozen solid. This same effect is also caused if a Cryo Vine is shot by any weapon. After about 10 seconds, the expended Cryo Vine will begin expanding to its initial size and has the potential of releasing another mist.