Doom is the main villain and final boss of Salamander 2. Little is known about him, other than he is another hive mind created by the bacterians. Doom have ressurrected the Salamander Force, leading them into a new attack against Gradius and Latis. The Vic Viper is sent, along with the new spacecraft Super Cobra to fight against Doom's forces, successfully defeating the invaders and destroying their base, along with Doom.