The EDEN Syndrome (ＥＤＥＮ (エデン)症候群 Eden Shūkōgun?) is a mysterious disease in Digimon Story: Cyber Sleuth. It is said to be caught by heavy users of Cyberspace EDEN. Although it's said to be caused by brain nerves being overloaded with data due to illegally modded "[[Digivice ()|Digivice]]s", as well as "Brain Jack" made by Hackers, its cause is unknown.