USS Mustin (DD-413) was a Sims-class destroyer of the United States Navy, the first Navy ship of that name, in honor of Captain Henry C. Mustin (1874–1923), a pioneer of naval aviation. Mustin was laid down on 20 December 1937 by Newport News Shipbuilding & Dry Dock Co., Newport News, Virginia; launched on 8 December 1938; sponsored by Mrs. Lloyd M. Mustin, daughter-in-law of Captain Mustin; and commissioned on 15 September 1939, Lieutenant Commander James S. Freeman in command.