Puzzle 491 CASP ROLL Puzzle 2 R0002 in Casp Roll R0002 in german wiki The target is a member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system. The corresponding UNIPROT accession code is Q6NW40. The structure of the target protein has been solved in complex with its receptor Neogenin (Q92859, residues 853 to 1052), for which experimental structures are available.