The Ndesu was a giant B.O.W. created by TRICELL as a counterpart to "El Gigante" of rural Spain. The beasts themselves were very similar. While El Gigante had only a single large Plaga parasite inside it, Ndesu was created with a number of smaller Type-2 Plagas along with the larger specimen - both of which house the larger around their spinal column. As an homage to its predecessor, Ndesu proceeded to crush Dave Johnson underfoot, similar to a Ganado, the first El Gigante Leon S. Kennedy encountered and killed.